Acute myeloid leukemia

Disease1 paper2 findings

Upstream

H3K9 methylation

downin human cells1downin mice1

1 study

H3K9 methylation decreases acute myeloid leukemia in human cells.
“Increasing H3K9 methylation reduces the leukemogenesis of both young and aged murine and patient-derived leukemic cells.”
Cellsin patient-derived leukemic cellsleukemic cell
Raising H3K9 methylation curbs leukemic stem cell proliferation · Cancers · 14 Sep 2026
H3K9 methylation decreases acute myeloid leukemia in mice.
“Increasing H3K9 methylation reduces the leukemogenesis of both young and aged murine and patient-derived leukemic cells.”
Animalsin both young and aged murine leukemic cellshematopoietic stem and progenitor cell
Raising H3K9 methylation curbs leukemic stem cell proliferation · Cancers · 14 Sep 2026

CellsPeer-reviewed28 Sep

Targeting this epigenetic modification in mouse models and patient samples reduces leukemogenesis in young and aged cells.

Cancers · Walter B et al.