Dabigatran
Intervention1 paper3 findingsPubChem 216210ChEBI 70752
- Animals1
Outcomes
3Stem cell differentiation
upin mouse cells1Very low certainty
1 study
Stem cell differentiation
upin mouse cells1Very low certainty
Dabigatran increases stem cell differentiation in mouse cells.
Cellsbone marrow mesenchymal stem cells
Dabigatran Attenuates Osteoporosis by Balancing Osteoblastogenesis and Osteoclastogenesis by Targeting PRKAB1 and RELA · Research (Washington, D.C.) · 4 Sep 2026
Osteoclast differentiation
downin mouse cells1Very low certainty
1 study
Osteoclast differentiation
downin mouse cells1Very low certainty
Dabigatran inhibits osteoclast differentiation in mouse cells.
CellsRANKL-inducedbone-marrow-derived macrophages
Dabigatran Attenuates Osteoporosis by Balancing Osteoblastogenesis and Osteoclastogenesis by Targeting PRKAB1 and RELA · Research (Washington, D.C.) · 4 Sep 2026
Bone loss
downin mice1Very low certainty
1 study
Bone loss
downin mice1Very low certainty
Dabigatran decreases bone loss in mice.
Animalsin ovariectomized and aged mouse models
Dabigatran Attenuates Osteoporosis by Balancing Osteoblastogenesis and Osteoclastogenesis by Targeting PRKAB1 and RELA · Research (Washington, D.C.) · 4 Sep 2026