Cuttlefish ink nanoparticle hydrogel

1. Cuttlefish ink nanoparticle hydrogel improves subchondral bone microarchitecture in rats.

   “This coordinated regulation of inflammation and senescence further improved subchondral bone microarchitecture and restored joint homeostasis in OA rats.”

   Animalsin OA ratssubchondral bone

   Cuttlefish ink nanoparticle hydrogels ameliorate osteoarthritis via concurrent inhibition of macrophage pyroptosis and chondrocyte senescence

   Journal of nanobiotechnology·25 Apr 2026

1. Cuttlefish ink nanoparticle hydrogel decreases osteoarthritis in rats.

   “mitigation of synovitis and cartilage erosion.”

   Animalsin OA ratsjoint

   Cuttlefish ink nanoparticle hydrogels ameliorate osteoarthritis via concurrent inhibition of macrophage pyroptosis and chondrocyte senescence

   Journal of nanobiotechnology·25 Apr 2026

More on Osteoarthritis

1. Cuttlefish ink nanoparticle hydrogel inhibits cellular senescence in rats.

   “leading to inhibition of Mφ pyroptosis, alleviation of chondrocyte senescence, and mitigation of synovitis and cartilage erosion.”

   Animalsin OA ratscartilage

   Cuttlefish ink nanoparticle hydrogels ameliorate osteoarthritis via concurrent inhibition of macrophage pyroptosis and chondrocyte senescence

   Journal of nanobiotechnology·25 Apr 2026

More on Cellular senescence

1. Cuttlefish ink nanoparticle hydrogel inhibits pyroptosis in rats.

   “leading to inhibition of Mφ pyroptosis, alleviation of chondrocyte senescence, and mitigation of synovitis and cartilage erosion.”

   Animalsin OA ratssynovial and cartilage tissues

   Cuttlefish ink nanoparticle hydrogels ameliorate osteoarthritis via concurrent inhibition of macrophage pyroptosis and chondrocyte senescence

   Journal of nanobiotechnology·25 Apr 2026

More on Pyroptosis

1. Cuttlefish ink nanoparticle hydrogel inhibits glycolysis in rats.

   “In vivo, intra-articular delivery of CIMNP/Alg hydrogels synchronously suppressed ROS-driven HIF-1α/glycolytic signaling in both synovial and cartilage tissues”

   Animalsin OA ratssynovial and cartilage tissues

   Cuttlefish ink nanoparticle hydrogels ameliorate osteoarthritis via concurrent inhibition of macrophage pyroptosis and chondrocyte senescence

   Journal of nanobiotechnology·25 Apr 2026

More on Glycolysis