Cancer therapy

1. Cancer therapy increases clonal hematopoiesis of indeterminate potential in humans.

   “clonal hematopoiesis-reflecting persistent genomic stress-appears enriched in survivors, particularly decades after therapy”

   Reviewdecades after therapy

   Decoding Early-Onset Aging After Cancer: Hallmarks, Biomarkers, and Future Directions for Childhood and Young Adult Survivorship

   Cancers·16 Feb 2026

More on Clonal hematopoiesis of indeterminate potential

1. Cancer therapy increases epigenetic age in humans.

   “Epigenetic age acceleration is consistently observed across multiple survivor cohorts and correlates with treatment exposures, lifestyle factors, and chronic health conditions”

   Reviewin CAYA cancer survivors

   Decoding Early-Onset Aging After Cancer: Hallmarks, Biomarkers, and Future Directions for Childhood and Young Adult Survivorship

   Cancers·16 Feb 2026

More on Epigenetic age

1. Cancer therapy raises the risk of cardiovascular disease in humans.

   “cancer treatments provoke biological changes that mirror, and may accelerate, physiological aging processes”

   Reviewin CAYA cancer survivors

   Decoding Early-Onset Aging After Cancer: Hallmarks, Biomarkers, and Future Directions for Childhood and Young Adult Survivorship

   Cancers·16 Feb 2026

More on Cardiovascular disease