University of Massachusetts Medical School

• Michael Lodato

  Associate Professor

• Heidi Tissenbaum

  Professor of Molecular, Cell and Cancer Biology

• Cole Haynes

  Professor of Molecular, Cell and Cancer Biology

• Hoa Nguyen

  Lead investigator

• Najihah Aziz

  Lead investigator

• Marcus Ruscetti

  Lead investigator

• Avijit Mallick

  Lead investigator

• Violeta Duran Laforet

  Lead investigator

• John Haran

  Lead investigator

Sources: umassmed.edu, profiles.umassmed.edu, openalex.org

• Tufts University

  Modelling the dynamics of spontaneous clonal hematopoiesis in pet dogs during cancer therapy (sub-award to UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL), usaspending_subaward/ASST_NON_R01CA294792_075/MQE2JHHJW9Q8, $139K, 2025, Aug 20, 2025

• Alzheimer's Association

  HSR-ADRD, Digital Storytelling to Promote Early Dementia Diagnosis in Rural Vietnam, 25HSR-ADRD-1487208, 2025, Jan 1, 2025

• American Heart Association

  Predoctoral Fellowship, CRISPR-edited thermogenic adipocytes as cell therapy for insulin resistance and cardiovascular risk in type 2 diabetes, 24PRE1192542, $67.4K, 2024–2025, Jan 1, 2024

• American Cancer Society

  Uncovering the heterogenous role of senescence in prostate immune suppression and tumorigenesis, RSG-23-1151969-01-IBCD, 792K, 2024–2027, Jan 1, 2024

• Natural Sciences and Engineering Research Council

  Postdoctoral Fellowships, Recovery of mitochondrial function in aged or degenerative tissues, 567544-2022, CA$45K, 2023–2024, Apr 1, 2023

• American Parkinson's Disease Association

  Single-cell whole genome sequencing analysis of DNA damage and somatic mutation in the human Parkinson's disease brain, 964374, 75K, 2022–2023, Sep 1, 2022

• BrightFocus Foundation

  Alzheimer's Disease Research: Postdoctoral Fellowship, Harnessing spatial transcriptomics to investigate the intersection of senescence and inflammation in neurodegeneration, A2022006F, $200K, 2022–2024, Jul 1, 2022

• Alzheimer's Association

  AARF, A Spatial Transcriptomic Approach to Interrogate Vascular-Associated Microglia in AD, AARF-22-923219, 2022, Jan 1, 2022

• Alzheimer's Association

  AARG, Single-Cell Analysis of DNA Damage and Mutation in Alzheimer's Disease, AARG-22-973134, 2022, Jan 1, 2022

• Alzheimer's Association

  AARG, Elderly microbiome dysbiosis, Alzheimer’s disease, and cognitive decline, AARG-19-641955, 2019, Jan 1, 2019

Sources: openalex.org

• Quantifying Effects of Diet and Lifestyle Changes on Progression to Advanced Age Related Macular Degeneration in High Genetic Risk Individuals

  Oct 10, 2025

• H50Q mutation in alpha-Synuclein impairs the insulin signaling pathway and induces neuroinflammation in the Drosophila model

  Feb 20, 2025

• Accumulation of F-actin drives brain aging and limits healthspan in Drosophila

  Oct 25, 2024

• Sex-Differential Markers of Psychiatric Risk and Treatment Response Based on Premature Aging of Functional Brain Network Dynamics and Peripheral Physiology

  Oct 16, 2024

• Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity

  Aug 11, 2022

• Supervised preoperative walking on increasing early postoperative stamina and mobility in older adults with frailty traits: A pilot and feasibility study

  Internal Funding, Jul 20, 2022

• Neuronal induction of BNIP3-mediated mitophagy slows systemic aging in Drosophila

  May 16, 2022

• Health effects of loneliness and social isolation in older adults living in congregate long term care settings: A systematic review of quantitative and qualitative evidence

  May 13, 2022

• Endoplasmic Reticulum Stress Induced Proliferation Remains Intact in Aging Mouse β-Cells

  Aug 31, 2021

• Macrophage LC3-associated phagocytosis is an immune defense against Streptococcus pneumoniae that diminishes with host aging

  Dec 21, 2020

• The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

  Aug 4, 2020

• Racial/Ethnic Disparities in Physical Function Before and After Total Knee Arthroplasty Among Women in the United States

  May 1, 2020

• Intestinal intermediate filament polypeptides in C. elegans: Common and isotype-specific contributions to intestinal ultrastructure and function

  Feb 21, 2020

• Age-and-sex stratified prevalence of atrial fibrillation in rural Western India: Results of SMART-India, a population-based screening study

  UL1-TR001453, Dec 6, 2018

• The Lifespan Human Connectome Project in Aging: An overview

  Oct 15, 2018

• Extending the Human Connectome Project across ages: Imaging protocols for the Lifespan Development and Aging projects

  Sep 24, 2018

• Functional status predicts postoperative mortality after liver transplantation

  Oct 20, 2016

• Systemic AAV9 gene transfer in adult GM1 gangliosidosis mice reduces lysosomal storage in CNS and extends lifespan

  May 10, 2015

Sources: api.crossref.org, openalex.org

• Predictive value of BMD for hip and other fractures: a meta-analysis to update FRAX

  Board or leadership role, Mar 12, 2026

• A meta-analysis of smoking and fracture risk to update the FRAX® tool

  Board or leadership role, Mar 4, 2026

• Family history of fracture and fracture risk: a meta-analysis to update the FRAX® risk assessment tool

  Board or leadership role, Aug 23, 2025

• Health Care Utilization and Costs for Older Adults Aging Into Medicare After the Affordable Care Act

  Fees or honoraria, Jan 3, 2025

• Previous fracture and subsequent fracture risk: a meta-analysis to update FRAX

  Board or leadership role, Aug 11, 2023

Sources: pubmed.ncbi.nlm.nih.gov

• Peripheral cytokine profiles contribute to machine learning model of frailty

  BMC geriatrics, Oct 29, 2026

• Long-term care study links stopping blood thinners to similar risks

  JAMA network open, Oct 26, 2026

• Weight Gain During Successful Tuberculosis Treatment Increases the Risk of Post-tuberculosis Metabolic Syndrome

  Open forum infectious diseases, Oct 25, 2026

• Whole genome sequencing identifies genetic variants associated with senescence-accelerated phenotype of OXYS rats

  Vavilovskii zhurnal genetiki i selektsii, Oct 23, 2026

• Researchers propose links between bone and nerve cell decline

  NPJ digital medicine, Oct 22, 2026

• Panagram reveals pangenome architectures underlying trait variation in plants and animals

  bioRxiv, Oct 22, 2026

• The cochlear macrophage in presbycusis: inflammaging, neuroinflammation, and targets for therapeutic modulation

  Frontiers in cellular neuroscience, Oct 18, 2026

• Hormone therapy linked to knee ligament tear risk in midlife women

  JB & JS open access, Oct 11, 2026

• Dietary Approaches to Stop Hypertension Diet Pattern and Metabolic Syndrome Prevalence Among U.S. Young Adults: Cross-Sectional Study From the NHANES 2011-2018

  Health science reports, Oct 9, 2026

• Epigenetic aging runs faster in larger and male dogs

  Science (New York, N.Y.), Oct 8, 2026

• Hearing Screening Among Underserved US Adults: A Scoping Review of Modalities and Determinants

  The Laryngoscope, Oct 8, 2026

• Alzheimer's disease neuropathological characterization of the dog brain and relationship to biofluid biomarkers and cognitive function

  NPJ dementia, Oct 8, 2026

• Balance deficits in people with HIV linked to brain volume and age

  Journal of acquired immune deficiency syndromes (1999), Oct 8, 2026

• Pathogenic modulators of cellular senescence

  Vavilovskii zhurnal genetiki i selektsii, Oct 2, 2026

• Age-Related Differences in Carbohydrate and Fat Oxidation Over 24 Hours and During Daily Activities in Humans

  bioRxiv, Sep 30, 2026

• Therapeutic potential of MitoQ, a mitochondria-targeted antioxidant, in age-related physiological dysfunction

  GeroScience, Sep 29, 2026

• Proteomic insights into childhood adversity: Exploring biological mechanisms and cognitive outcomes in the CARDIA study

  Brain, behavior, & immunity - health, Sep 28, 2026

• Retinal disease risk in electronic cigarette users versus combustible cigarette smokers: a retrospective cohort study

  AJO International, Sep 23, 2026

• Senolytic Interventions Enhance the Anti-metastatic Activity of Chemotherapy in Prostate Cancer

  Cancer research, Sep 21, 2026

• Beyond Traditional Glycemic Measures: CGM Glycemic Profiles Reveal Associations With Cardiometabolic Risk in Individuals Without Diabetes

  Diabetes care, Sep 17, 2026