Advanced Science
Tiny drug-carrying gels ease colitis in aged mice
In aged mice with chemically induced colitis, oral gels carrying an anti-inflammatory compound reduced disease severity and altered immune-cell responses.In aged mice with chemically induced colitis, oral gels carrying an anti-inflammatory compound reduced disease severity and altered immune-cell responses.
Mouse studyInterventions
Who was studiedAged female mice with colitis, through day 11, against untreated aged colitis mice
What changedColon inflammation scores were 2.6 with drug-carrying gels versus 7.4 in untreated aged mice
The catchOnly 6 mice per group in the treatment experiment