Apolipoprotein A
Apolipoprotein A has been studied in 3 papers since 2018: 3 observational studies in people. The newest paper, Oct 29, 2024: “Associations of Serum Lipid Traits With Fracture and Osteoporosis: A Prospective Cohort Study From the UK Biobank”.
3 papers study it2 findingsUpdated
See all 3 papers on apolipoprotein A
At a glance
The findings reach people, from one lab or study. 2 independent labs in 2 countries.
“Individuals in the highest quintiles for Apo A (fracture: HR 1.15 [95% CI 1.10, 1.21]”
None of its findings points the other way.
- 2 independent labs in 2 countries
- Funders: Innovation and Technology Commission - Hong Kong and 3 more
- 2 of 2 findings with company ties
- Humans3
What is apolipoprotein A linked with?
2Studies link apolipoprotein A with 2 measures, most often bone fracture (1 study) and dementia (1).
Bone fracture
upin humans1HR 1.15
1 study
Bone fracture
upin humans1HR 1.15
Apolipoprotein A is linked with a higher risk of bone fracture in humans (highest quintile) (HR 1.15 (95% CI 1.10-1.21)).
“Individuals in the highest quintiles for Apo A (fracture: HR 1.15 [95% CI 1.10, 1.21]”
Humanshighest quintile
Journal of cachexia, sarcopenia and muscle
Dementia
downin humans1HR 0.77
1 study
Dementia
downin humans1HR 0.77
Apolipoprotein A is linked with a lower risk of dementia in humans (highest versus lowest quarter) (HR 0.77 [0.69, 0.86]).
“highest quarter of ApoA was associated with lower dementia risk”
Humanshighest versus lowest quarter
EClinicalMedicine