Anti-bcl-xl senolytic
1 paper1 finding
- 1 lab in 1 country
- Funders: Guangdong Provincial Applied Science and Technology Research and Development Program and 4 more
- Animals1
Outcomes
1Metastatic melanoma
downin mice1
1 study
Metastatic melanoma
downin mice1
Anti-bcl-xl senolytic decreases metastatic melanoma in mice.
“A sequential strategy using cortactin depletion followed by an anti-Bcl-xL senolytic eliminated the persistent CTCs and suppressed blood-borne metastasis.”
Animalscortactin depletion followed by an anti-Bcl-xL senolytic
Cortactin Suppresses mTOR-Dependent Senescence in Circulating Tumor Cells
Cancer research19 Dec 2025
Latest
1 in 12 monthsCancer Research
Cortactin Suppresses mTOR-Dependent Senescence in Circulating Tumor Cells
Experiments in miceInterventions