CTTN

1 paper1 finding

HGNC NCBI Gene Taxon

1 lab in 1 country

Funders: Guangdong Provincial Applied Science and Technology Research and Development Program and 4 more

Animals1

Effects

1

Cellular senescence

downin human cells1

1 study

CTTN inhibits cellular senescence in human cells.
“Depletion of cortactin induced aberrant endosomal aggregates with mTOR accumulation and hyperactivation, subsequently leading to p53 activation, G0-G1 arrest, and cellular senescence.”
Cellsshown by depletion
Cortactin Suppresses mTOR-Dependent Senescence in Circulating Tumor Cells
Cancer research19 Dec 2025

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Cancer Research19 Dec

Cortactin Suppresses mTOR-Dependent Senescence in Circulating Tumor Cells

Experiments in miceInterventions