Adjuvant endocrine therapy

1. Adjuvant endocrine therapy raises the risk of diabetes mellitus in humans (absolute CI difference = 2.58% (95% CI: 0.02-5.14)).

   Humans5 yearsfemalesn = 8,365

   Endocrine therapy adherence and 10-year cardiometabolic risk in hormone receptor-positive breast cancer · JNCI cancer spectrum · 24 Sep 2026

Diabetes mellitus →

1. Adjuvant endocrine therapy raises the risk of dyslipidemia in humans (absolute CI difference = 5.16% (95% CI: 0.31-10.0)).

   Humans5 yearsfemalesn = 8,365

   Endocrine therapy adherence and 10-year cardiometabolic risk in hormone receptor-positive breast cancer · JNCI cancer spectrum · 24 Sep 2026

Dyslipidemia →

1. Adjuvant endocrine therapy raises the risk of hypertension in humans (absolute CI difference = 8.81% (95% CI: 4.25-13.4)).

   Humans5 yearsfemalesn = 8,365

   Endocrine therapy adherence and 10-year cardiometabolic risk in hormone receptor-positive breast cancer · JNCI cancer spectrum · 24 Sep 2026

Hypertension →