Adipose-derived stem cell exosomes

Intervention

4 papers9 findings

  • 3 independent labs in 1 country
  • Animals2
  • Cells2

Outcomes

4

Apoptosis

downin mouse cells2downin human cells1

3 studies
  1. Adipose-derived stem cell exosomes inhibit apoptosis in human cells.

    “inhibiting apoptosis and regulating collagen secretion, by regulating ER stress through SIRT1”

    Cellsin H2O2-treated fibroblasts

    Adipose-derived stem cell exosomes attenuated fibroblast senescence by regulating endoplasmic reticulum stress through SIRT1

    Tissue & cell20 Jan 2026

  2. Adipose-derived stem cell exosomes decrease apoptosis in mouse cells.

    “ADSCs-derived exosomes alleviated senescence and apoptosis of pGCs, while KLF3-AS1 depletion blocked these phenotypes.”

    Cells

    Adipose-derived stem cells exosomal KLF3-AS1 attenuates ovarian function by YBX1/PI3K/Akt/mTOR signaling

    Physiology international10 Apr 2025

  3. Adipose-derived stem cell exosomes decrease apoptosis in mouse cells.

    “ADSC-derived exosomes also mitigated senescence and apoptosis in pGCs, while circHIPK3 depletion hindered these benefits.”

    CellspGCsprimary granulosa cells

    Adipose-derived stem cells exosomal circHIPK3 protects ovarian function by regulating MAPK signaling

    Indian journal of pharmacology19 Feb 2025

More on Apoptosis

Cellular senescence

downin mouse cells3

3 studies
  1. Adipose-derived stem cell exosomes decrease cellular senescence in mouse cells.

    “ADSCs-derived exosomes alleviated senescence and apoptosis of pGCs, while KLF3-AS1 depletion blocked these phenotypes.”

    Cells

    Adipose-derived stem cells exosomal KLF3-AS1 attenuates ovarian function by YBX1/PI3K/Akt/mTOR signaling

    Physiology international10 Apr 2025

  2. Adipose-derived stem cell exosomes decrease cellular senescence in mouse cells.

    “ADSC-derived exosomes also mitigated senescence and apoptosis in pGCs, while circHIPK3 depletion hindered these benefits.”

    CellspGCsprimary granulosa cells

    Adipose-derived stem cells exosomal circHIPK3 protects ovarian function by regulating MAPK signaling

    Indian journal of pharmacology19 Feb 2025

  3. Adipose-derived stem cell exosomes decrease cellular senescence in mouse cells.

    “the light-treated ASCs-derived exosomes decrease the expression of senescence, SASP, and SA-β-Gal in the later passage cells.”

    Cellslater-passage cellsexosomes derived from light-treated adipose-derived stem cellsadipose-derived stem cell

    Photomodulation Alleviates the Senescence of Adipose-Derived Stem Cells Aging in Vitro

    Research Square7 Mar 2022Preprint

More on Cellular senescence

Follicular development

upin mice2

2 studies
  1. Adipose-derived stem cell exosomes improve follicular development in mice.

    “Treatment with ADSC-derived exosomes notably elevated the ovary weight and enhanced follicular development in aged mice”

    Animalsovaryfemales

    Adipose-derived stem cells exosomal KLF3-AS1 attenuates ovarian function by YBX1/PI3K/Akt/mTOR signaling

    Physiology international10 Apr 2025

  2. Adipose-derived stem cell exosomes improve follicular development in mice.

    “Treatment with these exosomes significantly increased ovary weight and enhanced follicular development in aged mice.”

    Animalsaging miceovaryfemales

    Adipose-derived stem cells exosomal circHIPK3 protects ovarian function by regulating MAPK signaling

    Indian journal of pharmacology19 Feb 2025

Ovary weight

upin mice1

1 study
  1. Adipose-derived stem cell exosomes increase ovary weight in mice.

    “Treatment with these exosomes significantly increased ovary weight and enhanced follicular development in aged mice.”

    Animalsaging miceovaryfemales

    Adipose-derived stem cells exosomal circHIPK3 protects ovarian function by regulating MAPK signaling

    Indian journal of pharmacology19 Feb 2025

More on Ovary weight

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