Adipose-derived mesenchymal stem cells

Intervention

3 papers2 findings

  • 2 independent labs in 2 countries
  • Funders: Natural Science Foundation of Guizhou Province and 2 more
  • Human trial1
  • Animals1
  • Cells1

Outcomes

2

Cholinesterase

downin humans1

1 study
  1. Adipose-derived mesenchymal stem cells decrease cholinesterase in humans (mean difference: -21.905 U/L, p < 0.001).

    “A paired samples t‐test revealed a statistically significant decrease in cholinesterase levels after ADSC administration (mean difference: ‐21.905 U/L, p < 0.001).”

    Human trialserumn = 21

    Immediate Effects of Adipose‐Derived Mesenchymal Stem Cell Administration on Cholinesterase Levels and Grip Strength

    AAIC 2025 abstract25 Dec 2025

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Osteoarthritis

downin mice1

1 study
  1. Adipose-derived mesenchymal stem cells decrease osteoarthritis in mice.

    “ADSC pretreatment with curcumin optimized the therapeutic effects on cartilage degeneration and matrix metabolism, synovial inflammation and subchondral bone deterioration”

    AnimalsDMM osteoarthritis modelmales

    Curcumin controls the senescence of adipose-derived mesenchymal stem cells via the FoxO3/autophagy signaling pathway to enhance joint homeostasis for osteoarthritis therapy

    Stem cell research & therapy30 Nov 2025

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