Adipose-derived mesenchymal stem cells
3 papers2 findings
- 2 independent labs in 2 countries
- Funders: Natural Science Foundation of Guizhou Province and 2 more
- Human trial1
- Animals1
- Cells1
Outcomes
2Cholinesterase
downin humans1
1 study
Cholinesterase
downin humans1
Adipose-derived mesenchymal stem cells decrease cholinesterase in humans (mean difference: -21.905 U/L, p < 0.001).
“A paired samples t‐test revealed a statistically significant decrease in cholinesterase levels after ADSC administration (mean difference: ‐21.905 U/L, p < 0.001).”
Human trialserumn = 21
AAIC 2025 abstract25 Dec 2025
Osteoarthritis
downin mice1
1 study
Osteoarthritis
downin mice1
Adipose-derived mesenchymal stem cells decrease osteoarthritis in mice.
“ADSC pretreatment with curcumin optimized the therapeutic effects on cartilage degeneration and matrix metabolism, synovial inflammation and subchondral bone deterioration”
AnimalsDMM osteoarthritis modelmales
Stem cell research & therapy30 Nov 2025
Latest
2 in 12 monthsAAIC 2025 Abstract
Immediate Effects of Adipose‐Derived Mesenchymal Stem Cell Administration on Cholinesterase Levels and Grip Strength
Non-randomised trial in 21 peopleInterventions
Stem Cell Research & Therapy
Curcumin controls the senescence of adipose-derived mesenchymal stem cells via the FoxO3/autophagy signaling pathway to enhance joint homeostasis for osteoarthritis therapy
Experiments in miceCurcumin
Cardiovascular Diabetology
Comparison of biological properties of human adipose tissue-derived mesenchymal stem/ stromal cells from healthy and diabetic donors: consequences for cell-based medicinal product development
Experiments in human cellsMechanisms