Wounds
Disease2 papers
Trial sponsors
Children's Surgical Center, Cambodia
1 trialPhase 2100 people
University of Campinas, Brazil
1 trialPhase 1/222 people
Universidade Estadual de Maringá
1 trialPhase 1/215 people
Funding
National Institute on AgingUS$1.3mNational Institute of General Medical SciencesUS$409.9kNational Institute of Child Health and Human DevelopmentUS$346.5k7 grants since 2021
A Drosophila model to understand the role of aging macrophages in epithelial wound healing
National Institute on AgingUniversity of California, BerkeleyUS$47.7k2026–2028
Targeting Senescence to Improve Wound Healing in Aging
National Institute on AgingBoston University Medical CampusUS$243k2023–2028
Rapid remodeling of the translatome underlying wound healing and regeneration
National Institute of Child Health and Human DevelopmentStanford UniversityUS$346.5k2022–2027
Protease Resistant Growth Factor Nanoparticles for Chronic Wound Healing
National Institute on AgingUniversity of South FloridaUS$353.4k2023–2028
Reprogramming cells for repair of chronic wounds
National Institute of General Medical SciencesUniversity of Michigan at Ann ArborUS$409.9k2026–2030
Aging Impairs Wound Healing by an HSC-Autonomous Mechanism
National Institute on AgingUniv of Massachusetts Med Sch WorcesterUS$626.4k2026–2031
Defining translational mechanisms to promote regenerative healing of chronic wounds
Latest
59Protein recycling decline hinders senescent cell clearance in mice
In experiments in mice, blocking a protein-recycling pathway in immune cells increased the build-up of senescent cells, which had stopped dividing.In experiments in mice, blocking a protein-recycling pathway in immune cells increased the build-up of senescent cells, which had stopped dividing.
SASP factors drive growth of altered cancer cells in culture
Using a microarray platform, researchers identified shared growth drivers in breast and lung cancer cells that required cellular alterations to…Using a microarray platform, researchers identified shared growth drivers in breast and lung cancer cells that required cellular alterations to promote proliferation.
Pathogenic modulators of cellular senescence
Aging impairs tentacle regeneration in Cladonema medusae
Aged Cladonema medusae show stem cell depletion, increased DNA damage, delayed wound closure, and defective blastema formation during tentacle repair.Aged Cladonema medusae show stem cell depletion, increased DNA damage, delayed wound closure, and defective blastema formation during tentacle repair.