Acetylglutamine

1. Acetylglutamine decreases CDKN1A in human cells.

   “attenuating p21 and p53 upregulation”

   Cellsin cyclophosphamide-injured KGN cells

   Integrative serum metabolite prioritization and functional screening identify N-acetyl-L-glutamine as a protective candidate in premature ovarian insufficiency

   Frontiers in genetics·2 Jul 2026

More on CDKN1A

1. Acetylglutamine decreases TP53 in human cells.

   “attenuating p21 and p53 upregulation”

   Cellsin cyclophosphamide-injured KGN cells

   Integrative serum metabolite prioritization and functional screening identify N-acetyl-L-glutamine as a protective candidate in premature ovarian insufficiency

   Frontiers in genetics·2 Jul 2026

More on TP53

1. Acetylglutamine decreases cellular senescence in human cells.

   “reducing the number of SA-β-gal-positive cells and the accumulation of ROS, and partially restoring the mitochondrial membrane potential”

   Cellsin cyclophosphamide-injured KGN cells

   Integrative serum metabolite prioritization and functional screening identify N-acetyl-L-glutamine as a protective candidate in premature ovarian insufficiency

   Frontiers in genetics·2 Jul 2026

More on Cellular senescence