Aav GATD3A gene therapy

1 paper1 finding

1 lab in 1 country

Funders: Nanjing Medical University and 1 more

Animals1

Outcomes

1

Osteoarthritis severity

downin mice1

1 study

Aav GATD3A gene therapy decreases osteoarthritis severity in mice.
“Intra-articular injection of recombinant adeno-associated virus carrying GATD3A significantly alleviates the osteoarthritis phenotype in male mice.”
Animalsosteoarthritisrecombinant adeno-associated virus carrying GATD3Amales
GATD3A-deficiency-induced mitochondrial dysfunction facilitates senescence of fibroblast-like synoviocytes and osteoarthritis progression
Nature communications30 Dec 2024

Latest

Nature Communications31 Dec

GATD3A-deficiency-induced mitochondrial dysfunction facilitates senescence of fibroblast-like synoviocytes and osteoarthritis progression

Experiments in miceOsteoarthritis