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4,5-dicaffeoylquinic acid

Intervention

1 paper1 finding

PubChemChEBI

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 2 more
  • Animals1

Outcomes

1

Osteoarthritis severity

downin mice1

1 study

  1. 4,5-dicaffeoylquinic acid decreases osteoarthritis severity in mice.

    “which disrupts the interaction between DPP4 and MYH9, thereby ameliorating post-traumatic and aging-induced OA in mice caused by DPP4 upregulation.”

    Animalspost-traumatic and aging-induced osteoarthritis caused by DPP4 upregulation

    Dipeptidyl Peptidase 4 (DPP4) Exacerbates Osteoarthritis Progression in an Enzyme-Independent Manner

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)16 Dec 2024

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