ZNF512B

1 paper2 findings

HGNC NCBI Gene Taxon

1 lab in 1 country

Funders: King Abdullah University of Science and Technology and 4 more
2 of 2 findings with company ties

Animals1

Effects

2

Senescence-associated secretory phenotype (SASP)

downin human cells1

1 study

ZNF512B inhibits senescence-associated secretory phenotype (SASP) in human cells.
“In contrast, ZNF512B promotes preferential DNA repair at regulatory genomic regions, limiting SASP induction.”
Cells
ZNF512B safeguards genome integrity at regulatory regions to repress the SASP and inflammation
Cell stem cell16 Jun 2026

More on Senescence-associated secretory phenotype (SASP)

Inflammation

downin humans1

1 study

ZNF512B decreases inflammation in humans.
“In vivo, ZNF512B overexpression reduces DNA damage and inflammation following acute liver injury.”
Animalsfollowing acute liver injuryliver
ZNF512B safeguards genome integrity at regulatory regions to repress the SASP and inflammation
Cell stem cell16 Jun 2026

More on Inflammation

Latest

1 in 12 months

Cell Stem Cell17 Jun

ZNF512B safeguards genome integrity at regulatory regions to repress the SASP and inflammation

Experiments in animalsSenescence-associated secretory phenotype (SASP)