tp53
GeneDanio rerio1 paper1 findingNCBI Gene 30590Taxon 7955
- Model organisms1
Effects
1Cellular senescence
is required forin zebrafish1
1 study
Cellular senescence
is required forin zebrafish1
tp53 is required for cellular senescence in zebrafish.
Animalsfor UHRF1 overexpression-induced senescencehepatocyte
UHRF1 levels drive distinct senescent states in zebrafish liver cells · EMBO reports · 28 Sep 2026
Latest
1Model organismsCellular senescence
UHRF1 levels drive distinct senescent states in zebrafish liver cells
High UHRF1 expression causes stable senescence sensitive to Navitoclax, while cells with lower expression proliferate if tp53 is mutated.