TFAM
GeneHomo sapiens1 paper1 findingHGNC 11741NCBI Gene 7019Taxon 9606
- Animals1
Associations
1Mitochondrial dysfunction
downin human cells1
1 study
Mitochondrial dysfunction
downin human cells1
TFAM is associated with mitochondrial dysfunction in human cells.
CellsagingCD8-positive, alpha-beta T cell
TFAM deficiency in T cells worsens viral lung pathology and weakens immunity · bioRxiv · 27 Sep 2026 · Preprint
Latest
2TFAM deficiency in T cells worsens viral lung pathology and weakens immunity
Declining TFAM levels impair mitochondrial function in CD8+ T cells, driving tissue damage and weakening long-term immune protection during influenza.