Sqstm1
GeneMus musculus5 papersMGI 107931NCBI Gene 18412Taxon 10090
- Animals5
Latest
5AnimalsPeer-reviewed
Dietary CoQ10 improves megakaryocyte function and reduces platelet hyperreactivity in aging mice
The supplement boosted autophagy via COPS3, enhancing megakaryocyte maturation and polyploidization without altering baseline platelet counts.
Aging cell · Xu Y et al.
Ghrelin alleviates aging-related cognitive impairment by restoring microglial autophagy
Researchers identified ghrelin as a key metabolic factor that reduces microglial senescence and inflammation through the SHBG/JNK1/Beclin1 signaling axis.
Aging cell · Zhou L et al.
Blocking Src kinase reduces neuroinflammation by activating microglial mitophagy in mice
Inhibiting the kinase reduced p62 UFMylation to promote ubiquitination and mitochondrial clearance, alleviating cognitive deficits in mice.
Biochemical pharmacology · Dong YR et al.
Hallmarks of Aging Associate with High Intensity Interval Training Benefits and Frailty in Female C57Bl/6J Mice
AnimalsThe journals of gerontology. Series A, Biological sciences and medical sciences
Protein kinase C θ deletion ameliorates bleomycin-induced pulmonary fibrosis via the improvement of SIRT1/AMPK signaling on autophagy and senescence
AnimalsIranian journal of basic medical sciences