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Cellular senescenceSenescent cells, the SASP, and the drugs that clear or quiet them.
Aging clocksEpigenetic, blood-based and other measures of biological age.
mTOR & rapamycinNutrient sensing through mTOR, and the rapalogs that dial it down.
Partial reprogrammingYamanaka factors, epigenetic reprogramming and cellular rejuvenation.
NAD+ & sirtuinsNAD+ precursors, sirtuins and the metabolism of aging cells.
MitochondriaMitochondrial function, mitophagy and energy decline with age.
Dietary restrictionCaloric restriction, fasting and time-restricted eating.
GLP-1 drugsSemaglutide, tirzepatide and what incretin drugs do to aging.
InflammagingChronic low-grade inflammation and the aging immune system.
Brain agingCognitive aging, neurodegeneration and the aging brain.

SLC5A2

GeneHomo sapiens1 paperHGNC 11037NCBI Gene 6524Taxon 9606

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Mitochondrial Dysfunction in Type 2 Diabetes and Metabolic Syndrome: Mechanisms, Biomarkers, and Emerging Therapies

ReviewDiabetes, Metabolic Syndrome and Obesity

·30 Sep

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Chronic inflammation1
Deregulated nutrient-sensing1
Disabled macroautophagy1
GLP-1 and incretin signalling1
GLP1R1
Insulin/IGF-1 signalling1
Mitochondrial dysfunction1
Mitophagy1
NAD+ metabolism1
Oxidative phosphorylation1
Oxidative stress and ROS signalling1
Metabolic syndrome1
Reactive oxygen species1
Type 2 diabetes1

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