Sirt1
GeneMus musculus6 papersMGI 2135607NCBI Gene 93759Taxon 10090
- Animals6
Latest
6Alda-1 Alleviates the Cognitive Deficits in D-galactose-induced Aging Mice by Regulating Oxidative Stress, Neuroinflammation, and Mitochondrial Biogenesis
AnimalsThe journals of gerontology. Series A, Biological sciences and medical sciences
Erigeron breviscapus extends worm lifespan and reduces senescence markers in mice
The herbal extract activates AMPK-SIRT1 signaling, enhancing antioxidant defenses and modulating apoptosis to alleviate tissue aging across both model organisms.
Biogerontology · Pu Y et al.
Activating Sirt1 reduces aortic valve calcification in mice and human cells
The sirtuin protects valves by activating the Nrf2 pathway, preserving mitochondrial function, and preventing iron-driven ferroptosis.
International journal of molecular medicine · Yan F et al.
Protein kinase C θ deletion ameliorates bleomycin-induced pulmonary fibrosis via the improvement of SIRT1/AMPK signaling on autophagy and senescence
AnimalsIranian journal of basic medical sciences