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Journal of Orthopaedic Translation·11 Mar

Mitochondrial metabolism restoration via Tramiprosate suppresses mitochondrial ROS-driven foamy macrophage senescence post spinal cord injury

Experiments in miceInterventions
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  • Basso Mouse Scale1
  • CGAS1
  • Cellular senescence1
  • DNA damage response1
  • Inflammation1
  • Lipid and ceramide metabolism1
  • Lipid droplet1
  • Mitochondrion1
  • Oxidative phosphorylation1
  • Oxidative stress and ROS signalling1
  • cGAS–STING signalling1
  • Foamy macrophages1
  • Gait analysis1
  • Matrix metalloproteinase activity1
  • Mitochondrial reactive oxygen species1
  • Motor evoked potentials1
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