Basso Mouse Scale

1. Nicotinamide riboside has no effect on Basso Mouse Scale in mice.

   “Functional recovery, lesion size (demyelinated (MBP), astrocyte (GFAP), and inflammatory (IBA1) area), and DNA damage load (γH2AX and PAR) did not improve with either Veliparib or NR treatment”

   Animalsspinal cord injuryspinal cord750 mg/kg28 days post-injuryfemales

   NAD⁺ supplementation and PARP inhibition following spinal cord injury in mice: Hurdles and considerations for therapeutic use

   Spinal cord·20 Aug 2026

More on Nicotinamide riboside

1. Veliparib has no effect on Basso Mouse Scale in mice.

   “Functional recovery, lesion size (demyelinated (MBP), astrocyte (GFAP), and inflammatory (IBA1) area), and DNA damage load (γH2AX and PAR) did not improve with either Veliparib or NR treatment”

   Animalsspinal cord injuryspinal cord25 mg/kg28 days post-injuryfemales

   NAD⁺ supplementation and PARP inhibition following spinal cord injury in mice: Hurdles and considerations for therapeutic use

   Spinal cord·20 Aug 2026

More on Veliparib