SFN
GeneHomo sapiens1 paper1 findingHGNC 10773NCBI Gene 2810Taxon 9606
- Animals1
Interventions
1Rapamycin
downin human cells1
1 study
Rapamycin
downin human cells1
Rapamycin decreases SFN in human cells.
CellsA549
Rapamycin slows pulmonary fibrosis by reducing lung epithelial cell senescence in mice · Research Square · 28 Sep 2026 · Preprint
Latest
1Rapamycin slows pulmonary fibrosis by reducing lung epithelial cell senescence in mice
The immunosuppressant suppresses epithelial-mesenchymal transition and promotes p53 degradation via the SFN-MDM2 pathway to curb fibrotic lung disease.