MIR23B

1. Valproic acid increases MIR23B in human cells.

   “Treatment with the demethylating agent valproic acid restored miR-23b-3p expression and facilitated its incorporation into EVs.”

   Cellsmesenchymal stem cells

   Aging-related changes of miR-23b-3p expression in extracellular vesicles from mesenchymal stromal cells affect TGFBR3 signaling

   Scientific reports·1 Jul 2025

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1. Icariin decreases MIR23B in human cells.

   “Icariin suppressed miR-23b-3p expression, and miR-23b-3p induction blocked the effects of icariin and promoted RTEC senescence.”

   Cellsurine exosome stimulation

   Icariin Attenuates Human Renal Tubular Epithelial Cell Senescence by Targeting PAK2 via miR-23b-3p

   Current pharmaceutical biotechnology·1 Jan 2024

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1. MIR23B decreases PAK2 in human cells.

   “Urine exosome stimulation up-regulated miR-23b-3p expression, which in turn suppressed PAK2 expression.”

   Cellsin HK-2 cells

   Icariin Attenuates Human Renal Tubular Epithelial Cell Senescence by Targeting PAK2 via miR-23b-3p

   Current pharmaceutical biotechnology·1 Jan 2024

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1. DNA methylation decreases MIR23B in human cells.

   “In aged MSCs, hypermethylation of the human MIR23B promoter region led to its downregulation.”

   Cellsin aged MSCsmesenchymal stem cells

   Aging-related changes of miR-23b-3p expression in extracellular vesicles from mesenchymal stromal cells affect TGFBR3 signaling

   Scientific reports·1 Jul 2025

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