H19

A preprint uses depletion experiments to link H19 to reduced senescence in mouse and human cells, reduced CDKN1A in human cells and improved viability in mice. All four findings come from one lab in one country and name the National Institutes of Health and U.S. Department of Health and Human Services as funders.

  • 1 lab in 1 country
  • Funders: National Institutes of Health and 1 more
  • Cells1
  • In silico1

Effects

3

Cellular senescence

downin human cells1downin mouse cells1

1 study
  1. H19 prevents cellular senescence in human cells.

    Cellsshown by depletion

    H19 lncRNA prevents cellular senescence through multiple controls on p21 mRNA

    Research Square5 Aug 2026Preprint

  2. H19 prevents cellular senescence in mouse cells.

    Cellsshown by depletion

    H19 lncRNA prevents cellular senescence through multiple controls on p21 mRNA

    Research Square5 Aug 2026Preprint

More on Cellular senescence

CDKN1A

downin human cells1

1 study
  1. H19 decreases CDKN1A in human cells.

    Cellsshown by depletion

    H19 lncRNA prevents cellular senescence through multiple controls on p21 mRNA

    Research Square5 Aug 2026Preprint

More on CDKN1A

Viability

upin mice1

1 study
  1. H19 improves viability in mice.

    Animalsshown by depletion

    H19 lncRNA prevents cellular senescence through multiple controls on p21 mRNA

    Research Square5 Aug 2026Preprint

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