H19
A preprint uses depletion experiments to link H19 to reduced senescence in mouse and human cells, reduced CDKN1A in human cells and improved viability in mice. All four findings come from one lab in one country and name the National Institutes of Health and U.S. Department of Health and Human Services as funders.
- 1 lab in 1 country
- Funders: National Institutes of Health and 1 more
- Cells1
- In silico1
Effects
3Cellular senescence
downin human cells1downin mouse cells1
1 study
Cellular senescence
downin human cells1downin mouse cells1
H19 prevents cellular senescence in human cells.
Cellsshown by depletion
H19 lncRNA prevents cellular senescence through multiple controls on p21 mRNA
Research Square5 Aug 2026Preprint
H19 prevents cellular senescence in mouse cells.
Cellsshown by depletion
H19 lncRNA prevents cellular senescence through multiple controls on p21 mRNA
Research Square5 Aug 2026Preprint
CDKN1A
downin human cells1
1 study
CDKN1A
downin human cells1
H19 decreases CDKN1A in human cells.
Cellsshown by depletion
H19 lncRNA prevents cellular senescence through multiple controls on p21 mRNA
Research Square5 Aug 2026Preprint
Viability
upin mice1
1 study
Viability
upin mice1
H19 improves viability in mice.
Animalsshown by depletion
H19 lncRNA prevents cellular senescence through multiple controls on p21 mRNA
Research Square5 Aug 2026Preprint