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DUSP6

Gene

5 papers study it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Centre Hospitalier Universitaire Vaudois and 4 more
  • Humans1
  • Animals1
  • Model organisms1
  • Cells1
  • In silico1

Associations

2

Physical decline

upin humans1

1 study

  1. DUSP6 is associated with physical decline in humans.

    “different associated loci (e.g., DUSP6 specific to physical Δ).”

    Humansgenome-wide association scan

    Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline

    Nature communicationsMay 15, 2025

Osteoarthritis

mixedin silico1

1 study

  1. DUSP6 is associated with osteoarthritis in silico.

    “further MR analysis identified four key marker genes (DUSP6, CSTA, CD300E, and GPX1) as causally related to OA, which was confirmed in an independent validation cohort.”

    In silicoMendelian randomization confirmed in independent validation cohort

    Comprehensive Multi-omics and Mendelian Randomization Reveal the Key Role of Monocytes in Aging and Osteoarthritis

    Molecular biotechnologyApr 2, 2025

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