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CSTA

Gene

2 papers study it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Guangzhou Municipal Science and Technology Project and 2 more
  • Animals1
  • In silico1

Interventions

1

Calcipotriol

upin mice1

1 study

  1. Calcipotriol increases CSTA in mice.

    “topical application of calcipotriol stimulates Csta production in the epidermis and alleviates osteoporosis.”

    Animalstopicalepidermis

    Skin chronological aging drives age-related bone loss via secretion of cystatin-A

    Nature aging

More on Calcipotriol

Effects

1

Bone loss

mediatesin mice1

1 study

  1. CSTA mediates bone loss in mice.

    “cystatin-A (Csta), a keratinocyte-enriched secreted factor, mediates the effect of skin on bone.”

    Animalsmediates effect of skin on bone

    Skin chronological aging drives age-related bone loss via secretion of cystatin-A

    Nature aging

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