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dTRABD

Gene

1 paper3 findings

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Fundamental Research Funds for the Central Universities and 1 more
  • Model organisms1

Effects

3

Tau toxicity

upin flies1

1 study

  1. dTRABD increases tau toxicity in flies.

    “dTRABD overexpression leads to neurodegeneration and enhances tau toxicity in fly eyes.”

    Model organismsdTRABD overexpressioneye

    TRABD modulates mitochondrial homeostasis and tissue integrity

    Cell reports5 Jun 2024

Neurodegenerative disease

upin flies1

1 study

  1. dTRABD induces neurodegenerative disease in flies.

    “dTRABD overexpression leads to neurodegeneration and enhances tau toxicity in fly eyes.”

    Model organismsdTRABD overexpression

    TRABD modulates mitochondrial homeostasis and tissue integrity

    Cell reports5 Jun 2024

More on Neurodegenerative disease

Lifespan

no changein flies1

1 study

  1. dTRABD has no effect on lifespan in flies.

    “Flies lacking dTRABD are viable and have normal lifespans.”

    Model organismsshown by loss of dTRABD

    TRABD modulates mitochondrial homeostasis and tissue integrity

    Cell reports5 Jun 2024

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