5 papers
Researchers identified PNPLA7 as an essential regulator of phosphatidylcholine catabolism necessary for maintaining mouse muscle fiber size and endurance.Researchers identified PNPLA7 as an essential regulator of phosphatidylcholine catabolism necessary for maintaining mouse muscle fiber size and endurance.
The compound lowered senescence markers and improved heart function through SIRT3-driven DRP1 deacetylation in aged mice and cultured cardiomyocytes.The compound lowered senescence markers and improved heart function through SIRT3-driven DRP1 deacetylation in aged mice and cultured cardiomyocytes.
Targeting ubiquinone biosynthesis counteracted reduced oxygen consumption and rescued lifespan loss caused by mitochondrial phosphatidylethanolamine deficiency in…Targeting ubiquinone biosynthesis counteracted reduced oxygen consumption and rescued lifespan loss caused by mitochondrial phosphatidylethanolamine deficiency in Caenorhabditis elegans.