AgingResearch.NewsJoin free

DCP2

Gene

3 papers2 findings

NCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Includes the processes named after it and trials of drugs aimed at it.

  • 2 independent labs in 2 countries
  • Funders: Anders Jahres Fond til Vitenskapens Fremme and 7 more
  • Humans1
  • Animals1
  • Model organisms1

Interventions

1

Caloric restriction

downin mice1

1 study

  1. Caloric restriction decreases DCP2 in mice.

    “Lastly, there was an age-associated increase in RNA degradation marker decapping enzyme 2 (DCP2) in UM-HET3 mice that was mitigated by CR.”

    Animalsin UM-HET3 miceskeletal muscle

    Skeletal muscle RBM3 expression is associated with extended lifespan in Ames Dwarf and calorie restricted mice

    Experimental gerontology30 Dec 2020

More on Caloric restriction

Associations

1

Pulse wave velocity

upin humans1

1 study

  1. DCP2 is associated with pulse wave velocity in humans.

    “DCP2 and XRN1 expression were positively associated with β-cell function at all timepoints and with pulse wave velocity at 5-year follow-up in women with previous GDM.”

    Humansin women with previous GDMfemales

    Oxidative stress, senescence and mRNA decay in peripheral blood mononuclear cells of women with gestational diabetes mellitus-link to increased cardiovascular disease risk

    Diabetes, obesity & metabolism17 Jun 2025

Latest

Related