Akh

Akh is required for protection from adverse metabolic outcomes in flies.

“We further demonstrate that adipokinetic hormone (AKH) is essential for the protective effects of trametinib under high-sugar conditions.”

Model organismsrequired for trametinib protection under high-sugar conditions

Pharmacological protection from a sugar-rich diet through inhibition of Ras/MAPK signaling

iScience·22 Sep 2026