CERS6
Gene2 papers4 findingsHGNC 23826NCBI Gene 253782Taxon 9606
A preprint reports that CERS6 promotes senescence in cultured podocytes and ageing marmosets; podocyte-specific deletion in ageing mice indicates that CERS6 promotes podocyte senescence and glomerulosclerosis.
- Animals2
Effects
3Cellular senescence
upin cells1upin marmosets1
1 study
Cellular senescence
upin cells1upin marmosets1
CERS6 induces cellular senescence in cells.
Cellscultured podocytes
Podocyte-specific CerS6 Drives Renal Aging via C16 Ceramide-mediated p53-p21 Senescence · Research Square · 21 Sep 2026 · Preprint
CERS6 induces cellular senescence in marmosets.
Animalsduring aging
Podocyte-specific CerS6 Drives Renal Aging via C16 Ceramide-mediated p53-p21 Senescence · Research Square · 21 Sep 2026 · Preprint
Glomerulosclerosis
upin mice1
1 study
Glomerulosclerosis
upin mice1
CERS6 increases glomerulosclerosis in mice.
Animalsshown by podocyte-specific deletion during aging
Podocyte-specific CerS6 Drives Renal Aging via C16 Ceramide-mediated p53-p21 Senescence · Research Square · 21 Sep 2026 · Preprint
Podocyte senescence
upin mice1
1 study
Podocyte senescence
upin mice1
CERS6 increases podocyte senescence in mice.
Animalsshown by podocyte-specific deletion during aging
Podocyte-specific CerS6 Drives Renal Aging via C16 Ceramide-mediated p53-p21 Senescence · Research Square · 21 Sep 2026 · Preprint