Severe urogenital infections

Disease1 paper1 finding

  • Humans1

Interventions

1

SGLT2 inhibitors

no changein humans1Low certainty

1 study

  1. SGLT2 inhibitors have no effect on severe urogenital infections in humans.

    Humansrequiring hospitalization or emergency department visits compared with DPP-4i

    SGLT2 inhibitors raise genital but not urinary infection risk · Clinical pharmacology and therapeutics · 28 Sep 2026

SGLT2 inhibitors →

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 1Oct 2026: 01
Clinical Pharmacology and TherapeuticsHumans

SGLT2 inhibitors raise genital but not urinary infection risk

In patients with diabetes and kidney disease, SGLT2 inhibitors carried an infection hazard ratio of 0.99 for UTIs and 1.31 for genital infections…In patients with diabetes and kidney disease, SGLT2 inhibitors carried an infection hazard ratio of 0.99 for UTIs and 1.31 for genital infections versus DPP-4 inhibitors.

Related