Pulmonary diseases
Disease1 paper
Latest
4AnimalsMitochondria
Prodh2 inhibition alleviates muscle atrophy and restores strength in COPD mice
TNF-alpha triggers a mitochondrial immune pathway via Prodh2 that damages myoblasts, while silencing the enzyme restores muscle strength in mice.
HumansInflammaging
Age-linked immune profiles identify distinct risk groups for chronic obstructive pulmonary disease
Clustering four age-associated inflammatory cytokines separated adults into three distinct endotypes tied to early chronic lung disease risk.