Pathological aging

Disease

2 papers study it520 more mention it

  • Animals1

Funding

7 grants since 2018

National Institute on AgingUS$5.3mNational Institute of Neurological Disorders and StrokeUS$5.8m

Latest

Nov 2025: 8Dec 2025: 5Jan 2026: 8Feb 2026: 4Mar 2026: 3Apr 2026: 8May 2026: 3Jun 2026: 5Jul 2026: 6Aug 2026: 5Sep 2026: 10Oct 2026: 267 papers in 12 months
bioRxiv

Cell counts may miss dementia-linked changes in human brains

An observational analysis of human brain tissue compared gene activity and cell proportions across normal cognition, disease-related aging and dementia.An observational analysis of human brain tissue compared gene activity and cell proportions across normal cognition, disease-related aging and dementia.

Preprint: study in peopleMechanisms
bioRxiv

Brain network control costs shift with age and Alzheimer's risk

In 279 older adults at risk for Alzheimer's disease, longitudinal changes in brain network control energy tracked cognitive performance and plasma p-tau181 levels.In 279 older adults at risk for Alzheimer's disease, longitudinal changes in brain network control energy tracked cognitive performance and plasma p-tau181 levels.

Preprint: cohort study of 279 peopleMechanisms
bioRxiv

Childhood ADHD brain patterns link to markers of late-life aging

In two human cohorts, Alzheimer's genetic risk predicted childhood ADHD, while an ADHD-related brain profile correlated with reproductive aging markers and poorer…In two human cohorts, Alzheimer's genetic risk predicted childhood ADHD, while an ADHD-related brain profile correlated with reproductive aging markers and poorer late-life cognition.

Preprint: cohort study of 522 peoplePopulations