Ovarian toxicity
3 papers study it4 more mention it
- Animals2
- Cells1
Funding
1 grant since 2018National Institute of Environmental Health SciencesUS$1.8m
Latest
2 papers in 12 monthsTissue & Cell
Perfluorodecanoic Acid (PFDA) induces ovarian toxicity and premature aging via mitochondrial dysfunction
Experiments in miceMitochondrion
Molecular and Cellular Biochemistry
Long-chain chlorinated paraffins exposure induces premature ovarian failure by disrupting the balance of mitochondrial fission
Experiments in mouse cellsMitochondrial fission and fusion
Ecotoxicology and Environmental Safety
Single-cell RNA sequencing across diverse cell types to identify PFOA-induced ovarian cellular senescence
Experiments in miceCellular senescence
Toxicological Research
Roundup® induces premature senescence of mouse granulosa cells via mitochondrial ROS-triggered NLRP3 inflammasome activation
Experiments in mouse cellsNLRP3 inflammasome
Drug and Chemical Toxicology
Cyclophosphamide, a cancer chemotherapy drug-induced early onset of reproductive senescence and alterations in reproductive performance and their prevention in mice
Experiments in miceReproductive system
Free Radical Biology & Medicine
Peroxiredoxin 2 deficiency accelerates age-related ovarian failure through the reactive oxygen species-mediated JNK pathway in mice
Experiments in animalsMechanisms