Decalepis hamiltonii

Decalepis hamiltonii improves reproductive outcome in mice.

“The results for the first time, demonstrate that the ovarian toxicity of CP could be prevented by an anti-oxidant to maintain a normal reproductive life span as well as reproductive outcome using mice model.”

Animalsco-treatment prior to CP administration

Cyclophosphamide, a cancer chemotherapy drug-induced early onset of reproductive senescence and alterations in reproductive performance and their prevention in mice

Drug and chemical toxicology·Jun 15, 2020

Decalepis hamiltonii prevents uterine endometrium regressive changes in mice.

“Further, the CP treated mice showed a significant increase in pre-coital interval and a significant reduction in parturition index coupled with regressive changes in the uterine endometrium, whereas DH co-treatment prevented these changes.”

Animalsco-treatment prior to CP administration

Cyclophosphamide, a cancer chemotherapy drug-induced early onset of reproductive senescence and alterations in reproductive performance and their prevention in mice

Drug and chemical toxicology·Jun 15, 2020

Decalepis hamiltonii improves reproductive life span in mice.

“treatment with the root extract of the herb Decalepis hamiltonii (DH) (200 mg/Kg bw/day for 7 days), a cocktail of anti-oxidants prior to CP administration maintained normal reproductive life span in mice.”

Animalsprior to CP administration200 mg/Kg bw/day7 days

Cyclophosphamide, a cancer chemotherapy drug-induced early onset of reproductive senescence and alterations in reproductive performance and their prevention in mice

Drug and chemical toxicology·Jun 15, 2020