Oral submucous fibrosis
- Animals1
Interventions
1Arecoline
upin mice1
1 study
Arecoline
upin mice1
Arecoline induces oral submucous fibrosis in mice.
“Finally, an arecoline-exposed OSF mouse model validated key in vivo aspects of this pathway, supporting its physiological relevance.”
Animalsarecoline exposure
Chemico-biological interactions30 Aug 2025
Trial sponsors
The Oxford Dental College, Hospital and Research Center, Bangalore, India
1 trialPhase 374 people
Services Institute of Medical Sciences, Pakistan
1 trialPhase 370 people
H.K.E.S's S.Nijalingappa Institute of Dental Science and Research
1 trialPhase 2200 people
SVS Institute of Dental Sciences
1 trialPhase 230 people
2 trialsPhase 1/275 people
Latest
Chemico-biological Interactions
YY1 lactylation promotes fibroblast senescence by targeting the PU.1-BTG2 axis to promote oral submucous fibrosis
Experiments in miceCellular senescence