2 papers
National Institute on Drug AbuseUS$408.2k
In mice with severe mitochondrial disease, a two-drug treatment extended median lifespan from 62 days to 158 days.In mice with severe mitochondrial disease, a two-drug treatment extended median lifespan from 62 days to 158 days.
Rates of dementia and Parkinson's disease were lower after surgery, with hazard ratios of 0.48 and 0.70 compared with matched people without surgery.Rates of dementia and Parkinson's disease were lower after surgery, with hazard ratios of 0.48 and 0.70 compared with matched people without surgery.
In a 35-year study, severe congenital heart disease had ≥2-fold higher comorbidity probabilities by age 40 than nonsevere cases, emerging two to three decades earlier.In a 35-year study, severe congenital heart disease had ≥2-fold higher comorbidity probabilities by age 40 than nonsevere cases, emerging two to three decades earlier.
For atherosclerotic cardiovascular disease, polygenic risk expanded the clinically identified high-risk subgroup by 40%, revealing patients with 4.9-fold higher incidence…For atherosclerotic cardiovascular disease, polygenic risk expanded the clinically identified high-risk subgroup by 40%, revealing patients with 4.9-fold higher incidence than those remaining low-risk.