Mammary tumours

3 papers2 findings

Animals3

Interventions

2

Rapamycin

no changein mice1

1 study

Rapamycin has no effect on mammary tumours in mice.
“with no impact on mammary and prostate tumours, and no effect on brain overgrowth”
Animalsheterozygous germline Pten losslow dose
Long-term treatment of cancer-prone germline PTEN mutant mice with low-dose rapamycin extends lifespan and delays tumour development
The Journal of pathology31 Oct 2022

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Levodopa

downin mice1

1 study

Levodopa decreases mammary tumours in mice.
“The chronic treatment of mice with L-dopa (2 mg/day) did not change these parameters and decreased the multiplicity of mammary tumours.”
Animalsmammary gland2 mg/day
Effect of treatment with phenformin, diphenylhydantoin or L-dopa on life span and tumour incidence in C3H/Sn mice
Gerontology1 Jan 1980

More on Levodopa

Latest

2 in 12 months

Cancer Control4 Sep

Voluntary Wheel Running Modulates Tumour-Associated Macrophage Polarization in Breast Cancer Lung Metastases of Old BALB/C Mice, in a Dose-dependent Manner

Experiments in miceLung

Nutrients28 Jul

Diets Rich in n-6 or n-3 Polyunsaturated Fatty Acids Combined with Exercise Influences Tumour Development in a Her-2 Breast Cancer Model

Experiments in 12 miceExercise

The Journal of Pathology31 Oct

Long-term treatment of cancer-prone germline PTEN mutant mice with low-dose rapamycin extends lifespan and delays tumour development

Experiments in miceRapamycin

Scientific Reports8 Jun

Booster immunizations with DNA plasmids encoding HER-2/neu prevent spontaneous mammary cancer in HER-2/neu transgenic mice over life span

Experiments in miceInterventions

Journal of Experimental Animal Science1 Jan

The tumor spectrum of Him:OFA rats

Experiments in ratsPopulations

Gerontology1 Jan

Effect of treatment with phenformin, diphenylhydantoin or L-dopa on life span and tumour incidence in C3H/Sn mice

Experiments in miceBiguanides

International Journal of Cancer15 Jun

The effect of long-term food restriction on tumours in rodents

Experiments in miceDietary restriction