Lupus erythematosus
1 paper1 finding
- Animals1
Upstream
1ZEB2
is required forin mice1
1 study
ZEB2
is required forin mice1
ZEB2 is required for lupus erythematosus in mice.
“In mice with toll-like receptor 7 (TLR7)-driven lupus, ZEB2 is essential for ABC formation and autoimmune pathology.”
Animalsin toll-like receptor 7-driven lupus mice
The transcription factor ZEB2 drives the formation of age-associated B cells
Science (New York, N.Y.)25 Jan 2024
Trial sponsors
Company1 trialPhase 462 people
Company1 trialPhase 220 people
Assistance Publique - Hôpitaux de Paris
1 trialPhase 1/210 people
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
1 trialPhase 1/21 person
Funding
6 grants since 2017NIH Clinical CenterNational Institute on AgingUS$381.2kNational Institute of Allergy and Infectious DiseasesUS$73.6k
National Institute of Allergy and Infectious DiseasesUniversity of PennsylvaniaUS$37.1k2023–2026
National Institute on AgingHospital for Special SurgeryUS$193.3k2024–2029
Japan Society for the Promotion of ScienceUniversity of TokyoJP¥18.9m2025–2028
Effect of interval training on serum adipokine levels in patients with systemic lupus erythematosus
Fundacao de Amparo a Pesquisa do Estado de Sao PauloFederal University of São Paulo2019–2022
Canadian Institutes of Health Research (CIHR) Project GrantDalhousie UniversityCA$17.5k2017–2018