Jak1/3 inhibitor
1 paper2 findings
- 1 lab in 2 countries
- Funders: Cancer Research UK and 5 more
- Animals1
Outcomes
1Age-associated B cells
downin humans1downin mice1
1 study
Age-associated B cells
downin humans1downin mice1
Jak1/3 inhibitor decreases age-associated B cells in humans.
“treatment with JAK1/3 inhibitor reduces ABC accumulation in autoimmune mice and patients.”
Human trialin autoimmune patients
The transcription factor ZEB2 drives the formation of age-associated B cells
Science (New York, N.Y.)25 Jan 2024
Jak1/3 inhibitor decreases age-associated B cells in mice.
“treatment with JAK1/3 inhibitor reduces ABC accumulation in autoimmune mice and patients.”
Animalsin autoimmune mice
The transcription factor ZEB2 drives the formation of age-associated B cells
Science (New York, N.Y.)25 Jan 2024
Latest
Science
The transcription factor ZEB2 drives the formation of age-associated B cells
Experiments in miceBlood and immune system