Lumbar disc herniation
2 papers3 findings
- Humans2
Associations
3LINC00638
upin humans1
1 study
LINC00638
upin humans1
LINC00638 predicts lumbar disc herniation in humans (AUC = 0.828, sensitivity 70.97%, specificity 80.56%).
“Low LINC00638 expression was identified as a reliable diagnostic indicator for LDH (AUC = 0.828, sensitivity 70.97%, specificity 80.56%, p < 0.001)”
HumansLDH diagnosisserum
JOR spine5 Dec 2025
Nucleus pulposus progenitor cells
downin humans1
1 study
Nucleus pulposus progenitor cells
downin humans1
Lumbar disc herniation is associated with nucleus pulposus progenitor cells in humans.
“cellular senescence and a decrease in nucleus pulposus progenitor cells (NPPCs) are central to both processes”
Humansnucleus pulposus
Single-nucleus transcriptomics decodes the link between aging and lumbar disc herniation
Protein & cell22 Mar 2025
Cellular senescence
upin humans1
1 study
Cellular senescence
upin humans1
Lumbar disc herniation is associated with cellular senescence in humans.
“cellular senescence and a decrease in nucleus pulposus progenitor cells (NPPCs) are central to both processes”
Humansnucleus pulposus
Single-nucleus transcriptomics decodes the link between aging and lumbar disc herniation
Protein & cell22 Mar 2025
Trial sponsors
University of Missouri-Columbia
1 trialPhase 4200 people
St Joseph University, Beirut, Lebanon
1 trialPhase 467 people
University Hospital Fattouma Bourguiba
1 trialPhase 460 people
1 trial108 people