Nucleus pulposus progenitor cells

Biomarker

1 paper1 finding

  • Humans1

Associations

1

Lumbar disc herniation

downin humans1

1 study
  1. Lumbar disc herniation is associated with nucleus pulposus progenitor cells in humans.

    “cellular senescence and a decrease in nucleus pulposus progenitor cells (NPPCs) are central to both processes”

    Humansnucleus pulposus

    Single-nucleus transcriptomics decodes the link between aging and lumbar disc herniation

    Protein & cell22 Mar 2025

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Science Advances

Layered gel improved spinal disc structure and function in rats

An experiment in rats with severe spinal disc degeneration found that a cell-carrying gel promoted new tissue formation and outperformed cells or a support scaffold…An experiment in rats with severe spinal disc degeneration found that a cell-carrying gel promoted new tissue formation and outperformed cells or a support scaffold alone.

Experiments in male Sprague-Dawley rats with disc degeneration, 8 weeksInterventions

Limit: Long-term repair and tissue fate after complete microsphere degradation remain untested