Lumbar disc degeneration
There are 4 papers on lumbar disc degeneration in aging research: 4 observational studies in people.
4 papers study it5 more mention it2 findings
“Degenerative discs showed elevated expression of hsa-miR-183-3p”
- Humans4
Upstream
1TNF-alpha
upin human cells1
1 study
TNF-alpha
upin human cells1
TNF-alpha increases lumbar disc degeneration in human cells.
“Degeneration of the intervertebral disc can be accelerated by TNF-α.”
Cellsintervertebral disc
Acta endocrinologica (Bucharest, Romania : 2005)
Associations
1Hsa-miR-183-3p
upin humans1
1 study
Hsa-miR-183-3p
upin humans1
Lumbar disc degeneration is associated with hsa-miR-183-3p in humans.
“Degenerative discs showed elevated expression of hsa-miR-183-3p”
Humansintervertebral disc
Acta endocrinologica (Bucharest, Romania : 2005)
Latest
2 papers in 12 monthsScientific Reports
Osteoporosis, spinal degenerative disorders, and their association with low back pain, activities of daily living, and physical performance in a general population
Cross-sectional study of 1,009 peopleLow back pain
Acta Endocrinologica
HSA-MIR-183-3P TARGETING ATAXIA-TELANGIECTASIA MUTATED PROTEIN REGULATION OF NF-ΚB SIGNALING PATHWAY AFFECTS CELLULAR SENESCENCE CAUSED BY DNA DAMAGE IN LUMBAR DISC DEGENERATION
Cross-sectional study in peopleNF-κB signaling
European Spine Journal
Is it appropriate to measure age-related lumbar disc degeneration on the mid-sagittal MR image? A quantitative image study
Cross-sectional study of 66 peopleBiomarkers
Journal of Orthopaedic Research
Microcalcification of lumbar spine intervertebral discs and facet joints is associated with cartilage degeneration, but differs in prevalence and its relation to age
Cross-sectional study of 85 peopleBones and joints
European Spine Journal
Age-referenced modeling of lumbar disc degeneration and its association with chronic low back pain: an MRI-based cross-sectional study
Cross-sectional study of 1,523 peopleChronic low back pain
BMC Musculoskeletal Disorders
Age- and sex-related differences in lumbar disc degeneration and multifidus muscle atrophy: a retrospective MRI study of 238 patients with chronic low back pain
Cohort study of 238 peopleLow back pain
European Spine Journal
Sex- and age-stratified analysis of structural risk factors for disabling chronic low back pain in a Japanese longitudinal cohort
Cohort study of 653 peopleChronic low back pain
European Spine Journal
Effective disc age: a statistical model for age-dependent and level-specific lumbar disc degeneration using magnetic resonance imaging (MRI)
Cross-sectional study of 84 peopleIntervertebral disc degeneration