Intestinal tumor

1. High-fat diet increases intestinal tumor in mice.

   “A 45% fat diet exacerbated bw and spontaneous tumor numbers versus 10% fat”

   Animalsin Apc(Min/+) mice

   Genetic and Diet-Induced Obesity Increased Intestinal Tumorigenesis in the Double Mutant Mouse Model Multiple Intestinal Neoplasia X Obese via Disturbed Glucose Regulation and Inflammation

   Journal of obesity·10 Aug 2015

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1. Heavy-ion radiation raises the risk of intestinal tumor in mice.

   “In Lgr5+Apc1638N/+ mice, tumor incidence was significantly higher in those exposed to 28Si radiation compared to the spontaneous tumorigenesis observed in control mice.”

   Animalsin Lgr5+Apc1638N/+ mice compared to control mice

   Effects of High-Linear-Energy-Transfer Heavy Ion Radiation on Intestinal Stem Cells: Implications for Gut Health and Tumorigenesis

   Cancers·4 Oct 2024

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