Gastro-oesophageal reflux disease

Disease1 paper1 finding

Humans1

Upstream

1

GLP1R

no changein silico1OR 0.97

1 study

GLP1R has no effect on gastro-oesophageal reflux disease in silico (OR 0.97, 95% CI 0.85-1.11).
“Genetically proxied GLP-1 receptor expression was not associated with reflux disease (odds ratio 0.97, 95% confidence interval 0.85-1.11)”
In silico
Genetic Assessment of Oesophageal Safety of GLP-1 and GIP Receptor Perturbation: A Drug-Target Mendelian Randomisation Study · Biomedicines · 24 Aug 2026

Latest

1

BiomedicinesHumans26 Sep

Genetic Assessment of Oesophageal Safety of GLP-1 and GIP Receptor Perturbation: A Drug-Target Mendelian Randomisation Study