Chronic inflammatory skin disease

Disease

2 papers2 findings

Effects

2

KL

downin humans1

1 study
  1. Chronic inflammatory skin disease decreases KL in humans.

    “reduced expression of longevity-related proteins like Klotho and SIRT1”

    Reviewin chronic inflammatory skin diseases

    Inflammation-Driven Molecular Ageing in Chronic Inflammatory Skin Diseases: Is There a Role for Biologic Therapies?

    Cells15 Sep 2025

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Oxidative stress and ROS signalling

upin humans1

1 study
  1. Chronic inflammatory skin disease increases oxidative stress and ROS signalling in humans.

    “Growing evidence links them to molecular and vascular ageing, including oxidative stress, endothelial dysfunction, and reduced expression of longevity-related proteins like Klotho and SIRT1.”

    Reviewin chronic inflammatory skin diseases

    Inflammation-Driven Molecular Ageing in Chronic Inflammatory Skin Diseases: Is There a Role for Biologic Therapies?

    Cells15 Sep 2025

More on Oxidative stress and ROS signalling

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